Zocor side effects
Zocor side effects
Zocor side effects has the generic name simvastatin. Zocor is a medication used to lower cholesterol, especially LDL cholesterol, and is a member of the class called statins. Zocor is available in 5 mg, 10 mg, 20 mg, 40 mg, and 80 mg doses. The 80 mg dose of Zocor is no longer adviced for patients who have not been on Zocor 80 mg for a year or more without Zocor side effects because of the higher incidence of myopathy in patients on Zocor 80 mg than on other statin regimens. Zocor additionally has FDA approval for the indications of mixed hyperlipidemia, dysbetalipoproteinemia, type for hyperlipidemia, homozygous familial hypercholesterolemia, and for prevention of adverse cardiovascular events in patients who are deemed to be high risk for cardiovascular events like heart attack due to diabetes, previously known coronary artery disease, or peripheral arterial disease. The risk of Zocor side effects is quite similar to the side effects of the Statin class in general.
Since June 2011 and FDA recommendation restricts Zocor 80 mg dosing to patients already taking Zocor 80 mg daily for a period of more than one year who have not already had myalgia side effects. The FDA now recommends limiting dosing of Zocor 40 mg daily. When patients on 40 mg Zocor are not at their goal LDL cholesterol adding a second lipid lowering medication or switching to a more potent statin is not recommended.
Myalgias are felt by many physicians to be the most common Zocor side effects. The severity of the myalgias may range from minor aching and pain to quite serious inflammation of the muscles, rhabdomyolysis with the potential for renal failure and even death. Zocor side effects of the gastrin trustable tract can include pain in the abdomen, diarrhea, flatulence, and constipation. URI symptoms and asthenia are some of the additional common Zocor side effects been reported.
Serious myopathy is the most common of the serious Zocor side effects. As is mentioned above this can be very serious Zocor side effects indeed. In less severe cases the myopathy is usually reversible and transient. As a general rule if the elevation of liver transaminase is more than thrice baseline levels Zocor dosing should be reduced or the medication stopped. Acute renal failure, pancreatitis, angioedema, anaphylaxis, and a type of lung disease called interstitial lung disease are potential Zocor side effects that can be serious. Serious skin related Zocor side effects may be Stevens Johnson syndrome, erythema multiforme, photosensitivity and toxic epidermal necrolysis. Disorders of the rheumatologic system can include polymyalgia rheumatica, lupus erythematosus, vasculitis and dermatomyositis. Leukopenia, hemolytic anemia and thrombocytopenia are some of the serious Zocor side effects of the hematologic system.
